Department of Pathophysiology with Course of Normal Physiology

Head of the Department:
Olha HANCHEVA, Professor, Doctor of Medical Sciences.


Historical Reference (Department of Pathophysiology)

The Department of Pathophysiology was established in 1965. At that time the Department carried out researches of blood supply of nuclei of a brain at various pathological states and influences on an organism of hypoxic trainings.

Since 1995, the Department has modernized approaches to teaching Pathophysiology using test control of knowledge, equipped a computer training class, a laboratory for computer image analysis, a class for watching educational films and multimedia presentations. There was also introduced a new direction of scientific research devoted to the definition of mechanisms of diabetes mellitus, hypertension and metabolic disorders, development of methods for their correction by brain neuropeptides and interval hypoxic training. The proposed methods allowed to reduce significantly the risk of complications in experimental diabetes and to develop effective approaches to their prevention.

Since 2016, the Department is headed by Professor Olha Hancheva.


Historical Reference (Course of Normal Physiology)

The Department of Anatomy and Physiology has been functioning at the Zaporozhye Pharmaceutical Institute since 1959. In 1965 the course of physiology was separated into an independent Department of Normal Physiology. At that time, an exemplary medical institute was established, which became one of the best in Ukraine.

From 1973 to 1985 one of the main research directions of the department was related to the regulatory mechanisms of intestinal absorption and secretory functions.

From 1985 to 2015, the department studied a formation of the mechanism of regulation of erythropoiesis in ontogenesis.

Since 2015 to 2021, the department was headed by Professor Oksana Kushch.


In 2020, the Department of Normal Physiology was reorganized into a Course of Normal Physiology to be merged with the Department of Pathophysiology.

In 2021, a new Department of Pathophysiology was established with a Course of Normal Physiology, headed by Professor Olha Hancheva.

Department of Pathophysiology with Course of Normal Physiology


Educational Disciplines

Pathophysiology — second- and third-year students of Medical Faculties Nos. 1, 2 and 3, Pharmaceutical Faculties Nos. 1 and 2, and International Faculty No. 2.

Normal Physiology — second-year students of Medical Faculties Nos. 1 and 2, and International Faculty No. 2.


Educational and Methodical Work

Domestic and foreign students (second and third years) of Medical Faculties, majoring in "Medicine", "Dentistry", "Pediatrics", "Laboratory Diagnostics", as well as domestic and foreign students (second and third years), majoring in "Pharmacy", "Physical Therapy, Occupational Therapy" and "Technology of Perfume-Cosmetic Preparations", study Pathophysiology at the Department; second-year students of all these specialties, except "Dentistry" and "Pharmacy", study Normal Physiology.

Methodical recommendations for practical classes of domestic and foreign students of Medical and Pharmaceutical Faculties, as well as a workshop for classroom and extracurricular work of students are issued.

Lecturers of the Department are constantly improving teaching methods. In 1997, for the first time at the University, the Department tested and implemented a rating system for students' knowledge assessment.

Multimedia presentations and videos are widely used during lectures and practical classes for visual presentation of educational material. Since 1999, in order to bring the theoretical knowledge of students to the practical activities of the doctor as close as possible, during practical classes the Department uses a set of modern diagnostic equipment (CardioLab, ReoCom, SpiroCom) to determine the parameters of cardiohemodynamics, cardiointervalometry and spirography with subsequent computer processing and analysis.

In 2000, a computer class and a modern test program UTSYS were created to teach and control students' knowledge.

In 2011, in accordance with the regulations on the Ministry of Health of Ukraine, approved by the Decree of the President of Ukraine No. 467/2011 dated April 13, 2011, and in connection with the introduction of new curricula for doctors of all specialties in higher medical educational institutions of the IV level of accreditation, the Department was appointed a base in the disciplines of undergraduate training in the specialties "Medicine", "Pediatrics", "General Medicine".


Scientific Directions and Achievements

The series of studies is devoted to the study of the subtle mechanisms of development of arterial hypertension, diabetes mellitus, heart failure. The Department developed and patented new methods of treatment of diabetes, hypertension, which can allow to reduce significantly the risk of complications and to develop effective methods of prevention of these diseases.

Confirmation of the expediency of these scientific areas of work of the department is the targeted funding of the Ministry of Health of Ukraine and the receipt of grants from the International Science Foundation. The Department has been conducting research work within the framework of the European Community's INTAS program since 2004. Also, some employees of the Department are members of the European Society of Cardiology.

Lecturers of the Department have published 6 monographs, more than 760 scientific works, of which more than 70 — in foreign publications, and received 27 patents for utility models.


Cooperation with Other Institutions

The Department maintains close scientific ties with research institutes of Kyiv (Bogomolets Institute of Physiology of the NAS of Ukraine), Kharkiv (Institute of Endocrine Pathology), as well as scientists from the USA and Germany.

The Department is a base for clinical testing of medical equipment, developed in conjunction with the Kharkiv Aviation Institute.


Address: 31 Stalevariv St., Zaporizhzhia, 69035, Ukraine

Telephone: +380 61 233 37 97

69035, Maiakovskyi avenue 26, Zaporizhzhia, Ukraine
Tel: +380 (61) 224-63-91 Fax: +380 (61) 233-60-07,       Send e-mail

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